UTSA Neurosciences Institute

One UTSA Circle San Antonio TX 78249

Hosted by CBI

> Lecture Series

April 10, 2017

UC Ballroom I

1604 Campus


5:00p Reception

5:30p Lecture

2017 Distinguished Public Lecture

A Strategy for Slowing the Progression of Parkinson’s Disease

D. James Surmeier PhD

Chair, Department of Physiology

Nathan Smith Davis Professor of Physiology

Director of the Morris K. Udall Research Center of Excellence for Parkinson's Disease

Feinberg School of Medicine, Northwestern University

Parkinson’s disease is the second most common neurodegenerative disorder in the U.S.  There are no proven strategies for preventing it or slowing its progression. But there is hope that a new treatment is on the horizon.

This talk will outline the rationale for a large Phase 3 clinical neuroprotection trial in early stage Parkinson’s disease patients with the drug isradipine that is being sponsored by the National Institutes of Health. The core idea behind the trial is that some neurons in the brain act as look-outs or sentries – they are always watching for events that could hurt or help us – and that this constant vigilance causes them to wear out as we age. The goal of the drug therapy is to remodel these neurons in a way that allows them to ‘take a break’ and rest without compromising their ability to do their job in the less threatening, more predictable world we live in today.   

Dr. Surmeier's research program focuses on the ionic mechanisms underlying neural activity in the basal ganglia and how this altered in Parkinson’s disease.  His recent identification of L-type Ca2+ channels as potential determinants of selective neuronal vulnerability in Parkinson’s disease has led to an NIH-sponsored Phase III clinical trial with the drug isradipine.

Click image for driving directions

UT Health parking tag holders have free parking privilege at UTSA in most cases.  Please see here for details of reciprocity.

A limited number of free surface parking tags will be available.  Request yours by March 27 here.  First come, first serve.

Parking for the public is available at the Ximinez Avenue Garage, at a rate of $2/hr.

No Registration Required, Free and Open to the Public